Sodium Chromate Cr 51 Injection

Sodium Chromate Cr 51 Injection

Mallinckrodt Inc.

Sodium Chromate Cr 51 Injection

NFPA

0
1 0

MSDS Name: Sodium Chromate Cr 51 Injection
Manufacturer Name: Mallinckrodt Inc.
Address:
2703 Wagner Place
Maryland Heights, MO 63043

Emergency Telephone Number: 314-654-7860

CANUTEC: 613-996-6666
Business Phone: (888) 744-1414
For information in North America, call: (888) 744-1414
Chemtrec: For emergencies in the US, call CHEMTREC: 800-424-9300
Manufacturer MSDS Revision Date: January 1, 2003
Synonyms:
Sodium Chromate; Sodium Chromate Cr 51; Chromium 51.
General Use:
Product Use: Diagnostic imaging agent

NFPA

Health: 1
Flammability: 0
Reactivity: 0
Other:
SECTION 3 : HAZARDS IDENTIFICATION
Emergency Overview:
CAUTION! RADIOACTIVE MATERIAL. Read package insert prior to use. Promptly remove any contamination from the skin, eyes, or clothing. Radioactive drugs must be handled by qualified personnel in conformity with regulations appropriate to the government agency authorized to license the use of this radionuclide. The vial containing the drug should be kept within its container or within heavier shielding. Avoid contact with the radioactive contents which would cause unnecessary exposure to radiation.
Applies to all ingredients:
Potential Health Effects:
Eye Contact:
No adverse effect expected, but may cause mechanical irritation.
Skin Contact:
Not expected to produce any acute adverse health effects.
Inhalation:
Not expected to be a health hazard via inhalation.
Ingestion:
May cause asymptomatic physiological uptake by specific target organs or tissues.
Chronic Health Effects:
The health risks associated with chronic radiation exposure (cancer, leukemia, genetic and teratogenic effects) are believed to involve levels of radiation exposure which are much higher than those permitted occupationally.
Aggravation of Pre-Existing Conditions:
No information found.
Sodium Chromate Cr 51:
Potential Health Effects:
Inhalation:
Sodium chromate does not easily become airborne.
SECTION 4 : FIRST AID MEASURES
Eye Contact:
If a splash occurs, wash eyes with water for at least 15 minutes or until no more radioactivity can be removed. Notify radiation safety personnel.
Skin Contact:
If skin contact occurs, wash the affected area thoroughly with soap and water until no more radioactivity can be removed. Always blot dry. Do not abrade skin. Notify radiation safety personnel.
Inhalation:
Not expected to require first aid measures.
Ingestion:
Notify radiation safety personnel immediately. The amount of material ingested should be assessed and documented.
SECTION 5 : FIRE FIGHTING MEASURES
Fire:
Not considered to be a fire hazard.
Explosion:
Not considered to be an explosion hazard.
Extinguishing Media:
Use any means suitable for extinguishing surrounding fire.
Fire Fighting Instructions:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
SECTION 6 : ACCIDENTAL RELEASE MEASURES
Spill Cleanup Measures:
If the product is received in a leaking condition or any loss or release of the radioactive contents occurs, notify your Radiation Safety Department and Mallinckrodt at (314) 654-7860. All cleanup operations should be performed according to the Standard Operating Procedures (SOPs) established for your facility and by the NRC or other applicable local, state or federal regulations.
SECTION 7 : HANDLING and STORAGE
Handling:
Handling time should be kept to a minimum and appropriate shielding should be used. Handling devices such as syringe shields and tongs should be used.
Storage:
Store at 15 deg C to 30 deg C.
Storage and disposal of product should be controlled in a manner which is in compliance with the appropriate regulations of the federal or state government agency authorized to license the use of this radionuclide.
SECTION 8 : EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Properly sealed containers are not expected to require any special ventilation.
Skin Protection Description:
Disposable plastic, latex, or rubber gloves; labcoat.
Eye/Face Protection:
Safety glasses.
Respiratory Protection:
Not expected to require personal respirator usage.
Exposure Limits:
Airborne: NRC Occupational concentration limit is 2x10^-5 µCi/mL of air.

Precaution:
No smoking, eating, or drinking should be allowed in any area where radioactive materials are handled or stored.
SECTION 9 : PHYSICAL AND CHEMICAL PROPERTIES
Physical State/Appearance:
Clear liquid.
Color:
Colorless
Odor:
Odorless.
Boiling Point:
ca. 100 deg C (212 deg F).
Melting Point:
ca. 0 deg C (32 deg F).
Solubility:
Soluble in water.

Radioactivity: 250 µCi as of the calibration date and time.

Concentration: 100 µCi/mL as of the calibration date and time.

Specific Activity: > 10 mCi/mg of sodium chromate on the calibration date and time.

Half Life: ca. 27.7 days.
SECTION 10 : STABILITY AND REACTIVITY
Chemical Stability:
Stable under ordinary conditions of use and storage.
Incompatibilities with Other Materials:
No information found.
Hazardous Polymerization:
Will not occur.
Hazardous Decomposition Products:
May emit radioactive fumes containing Cr-51 when heated to decomposition.
SECTION 11 : TOXICOLOGICAL INFORMATION
Toxicological Paragraph:
It is widely accepted by the scientific community that exposure to sufficient quantities of ionizing radiation can potentially cause harmful biological effects which include cancer, leukemia, and genetic and teratogenic effects. For detailed toxicological information on specific components, write to the address listed in Section 1 - Attn: Regulatory Compliance Department.
SECTION 12 : ECOLOGICAL INFORMATION
Ecological Paragraph:
Because this product is intended for use by hospital or clinic patients, it is expected to be treated by standard wastewater treatment facilities with no adverse environmental impacts.
SECTION 13 : DISPOSAL CONSIDERATIONS
Waste Disposal:
Sodium Chromate Cr 51 Injection is Radioactive Waste until the activity has decayed to nondetectable levels. Radioactive waste must be handled in accordance with procedures established by your Radiation Safety Officer, NRC and other applicable regulations.

If medical waste is involved, such as blood, blood products, or sharps, the waste must be handled as a Biohazard and disposed of accordingly.

If not radioactive or a biohazard, waste Sodium Chromate Cr 51 Injection is considered non-hazardous. Consult local, state and federal regulations for proper disposal.
RCRA Hazard Class:
RCRA Hazardous Waste Status: Non-hazardous
SECTION 14 : TRANSPORT INFORMATION
DOT Shipping Name:
Radioactive Material, excepted package-limited quantity of material
DOT Hazard Class: 7
DOT Identification Number: UN2910
SECTION 15 : REGULATORY INFORMATION

Applies to All Ingredients:

Section 302:
None
Section 304:
Releases to air, land or water of these hazardous substances which exceed the Reportable Quantity (RQ) must be reported to the National Response Center at 800-424-8802.
Section 312 Hazard Category:
311/312 Hazard Categories:
Chronic: Yes
State:
California Proposition 65 Warning: This product contains a substance known to the State of California to cause cancer.
Canada WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.
Australia Hazchem Code: None allocated.
Australia Poison Control Code: Schedule: None allocated.

RCRA Hazardous Waste Status:
Non-hazardous (See Section 13 for additional details).

Sodium Chromate Cr 51:

Section 304 CERCLA RQ: 1000 Ci (3.7 E 13 Bq)
Section 313 Toxic Release Form:
313 Toxic substances subject to annual release reporting requirements: Chromium Compounds.
SECTION 16 : ADDITIONAL INFORMATION
NFPA:
Fire Hazard: 0
Health: 1
Reactivity: 0
MSDS Revision Date:
January 1, 2003

Revision Information: Section 8 updated.

MSDS Status: Revised in accordance with ANSI Guideline Z400.1-1998
Disclaimer:
Mallinckrodt provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.

Product Use:
Diagnostic imaging agent

Tyco/Healthcare

Copyright© 1996-2005 Actio Software Corporation. All Rights Reserved.
ads

Health